Ultrasound, cavitation bubbles and their interaction with cells.
نویسندگان
چکیده
This article reviews the basic physics of ultrasound generation, acoustic field, and both inertial and non-inertial acoustic cavitation in the context of localized gene and drug delivery as well as non-linear oscillation of an encapsulated microbubble and its associated microstreaming and radiation force generated by ultrasound. The ultrasound thermal and mechanical bioeffects and relevant safety issues for in vivo applications are also discussed.
منابع مشابه
An overview of therapeutic applications of ultrasound based on synergetic effects with gold nanoparticles and laser excitation
Acoustic cavitation which occurs at high intensities of ultrasound waves can be fatal for tumor cells. The existence of dissolved gases and also the presence of nanoparticles (NPs) in a liquid, irradiated by ultrasound, decrease the acoustic cavitation onset threshold and the resulting bubbles collapse. On the other hand, due to unique capabilities and optical properties of gold nanoparticles (...
متن کاملJ. Gen. Appl. Microbiol., 52, 295–301 (2006)
an adjuvant to antimicrobial therapy, targeted at both planktonic and biofilm (sessile) organisms. Our previous work showed that ultrasound (US) effectively enhances the bactericidal activity of certain antibiotics against planktonic cultures (Pitt et al., 1994; Rediske et al., 1999) and in vitro biofilms (Johnson et al., 1998; Qian et al., 1999) and in vivo biofilms (Carmen et al., 2004b, 2005...
متن کاملApplication of analyzer based X-ray imaging technique for detection of ultrasound induced cavitation bubbles from a physical therapy unit
BACKGROUND The observation of ultrasound generated cavitation bubbles deep in tissue is very difficult. The development of an imaging method capable of investigating cavitation bubbles in tissue would improve the efficiency and application of ultrasound in the clinic. Among the previous imaging modalities capable of detecting cavitation bubbles in vivo, the acoustic detection technique has the ...
متن کاملEffect of Ultrasonication on Membrane Structure and Flux Recovery for Whey Ultrafiltration
In this study, the effect of ultrasound irradiation on the flux recovery and fouling mitigation for the membranes made of the polysulfone by the phase inversion method were investigated. Two ultrasound irradiation regimes, including inside and outside the module, were chosen for this study. The experiments were conducted to investigate the effect of ultrasound irradiation on the membrane struct...
متن کاملNumerical Solution for Gate Induced Vibration Due to Under Flow Cavitation
Among the many force s to which hydraulic structures are exposed to, the forces induced by cavitation incident are of typical hydrodynamic unknown forces. The aim of this study is to define these forces as coupled fluid-structure interaction under two dynamic effects. The first dynamic effect which incorporates facilities for dealing with cavitation fluid is based on the appearance and bursting...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Advanced drug delivery reviews
دوره 60 10 شماره
صفحات -
تاریخ انتشار 2008